Lion Blessé de Fotouni will play next season in the MTN Elite Two championship after they failed to escape relegation in the 2016-2017 football season.
They are the second team to be relegated this year after Canon of Yaounde.
Despite a 0-0 draw on Thursday against Colombe of South, the club from Fotouni still suffered relegation.
Out of 33 games played, Lion Blesse have recorded just 28 points and thus relegated to the second top flight football in the country.
Meanwhile, Racing or Astres Of Douala will join Lion Blesse and Canon in the relegation zone.